Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn’s Disease

Human gut development requires the orchestrated interaction of differentiating cell types. Here, we generate an in-depth single-cell map of the developing human intestine at 6–10 weeks post-conception. Our analysis reveals the transcriptional profile of cycling epithelial precursor cells; distinct f...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Elmentaite, Rasa, Ross, Alexander D.B., Roberts, Kenny, James, Kylie R., Ortmann, Daniel, Gomes, Tomás, Nayak, Komal, Tuck, Liz, Pritchard, Sophie, Bayraktar, Omer Ali, Heuschkel, Robert, Vallier, Ludovic, Teichmann, Sarah A., Zilbauer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762816/
https://ncbi.nlm.nih.gov/pubmed/33290721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.11.010
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