STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17

In tauopathies, memory impairment positively strongly correlates with the amount of abnormal tau aggregates; however, how tau accumulation induces synapse impairment is unclear. Recently, we found that human tau accumulation activated Signal Transduction and Activator of Transcription-1 (STAT1) to i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Signal Transduct Target Ther
Main Authors: Hong, Xiao-Yue, Wan, Hua-Li, Li, Ting, Zhang, Bing-Ge, Li, Xiao-Guang, Wang, Xin, Li, Xiao, Liu, Qian, Chen, Chong-Yang, Yang, Ying, Wang, Qun, Li, Shu-Peng, Yu, Hao, Wang, Jian-Zhi, Yang, Xi-Fei, Liu, Gong-Ping
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762755/
https://ncbi.nlm.nih.gov/pubmed/33361763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00290-9
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki