Determination of Crizotinib in Mouse Tissues by LC-MS/MS and Its Application to a Tissue Distribution Study

Toxicity induced by crizotinib, a small-molecule tyrosine kinase inhibitor, is a significant clinical issue during treatment. A tissue distribution study is required to explore the organs affected by this molecule. In this study, a simple liquid chromatography tandem mass spectrometry method was dev...

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Bibliografiska uppgifter
I publikationen:Int J Anal Chem
Huvudupphovsmän: Zhao, Fang, Wei, Yuan, Yan, Yiming, Liu, Han, Zhou, Sitong, Ren, Bo, Liu, Ruijuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762669/
https://ncbi.nlm.nih.gov/pubmed/33381185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8837254
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