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The Weaned Pig as a Model for Doxorubicin-Induced Mucositis

BACKGROUND: Chemotherapy-induced mucositis (CIM) complicates cancer therapy and limits maximum tolerated doses and efficacy. Rodent models do not reproducibly mimic clinical CIM, so alternative models are needed. METHODS: CIM severity was assessed after weaned pigs were treated with doxorubicin (5 a...

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Detalhes bibliográficos
Publicado no:Chemotherapy
Main Authors: Martin, Jamee, Howard, Scott C., Pillai, Asha, Vogel, Peter, Naren, Anjaparavanda P., Davis, Steven, Ringwald- Smith, Karen, Buddington, Karyl, Buddington, Randal K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762628/
https://ncbi.nlm.nih.gov/pubmed/25341697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000365725
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