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The Role of Copper (II) on Kininogen Binding to Tropomyosin in the Presence of a Histidine–Proline-Rich Peptide

The antiangiogenic activity of the H/P domain of histidine–proline-rich glycoprotein is mediated by its binding with tropomyosin, a protein exposed on endothelial cell-surface during the angiogenic switch, in presence of zinc ions. Although it is known that copper ion serum concentration is signific...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Santoro, Anna Maria, Zimbone, Stefania, Magrì, Antonio, La Mendola, Diego, Grasso, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762548/
https://ncbi.nlm.nih.gov/pubmed/33302425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249343
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