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Extracellular vesicle derived miR-544 downregulates expression of tumor suppressor promyelocytic leukemia zinc finger resulting in increased peritoneal metastasis in gastric cancer

Peritoneal metastasis (PM) is the main cause of poor prognosis in patients with advanced gastric cancer (GC). Increasing evidence has suggested that cancer-associated EVs in body fluids may assist in the diagnosis and treatment of GC. Here, we investigated the role of GC-derived EVs in PM developmen...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging (Albany NY)
Main Authors: Kong, Wencheng, Liu, Xinchun, Yin, Guang, Zheng, Sixin, Zhu, Akao, Yu, Panpan, Shan, Yuqiang, Ying, Rongchao, Zhang, Jian
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762464/
https://ncbi.nlm.nih.gov/pubmed/33221764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104082
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