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Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway

The expression of Hic-5 was detected in osteosarcoma patients and osteosarcoma cell lines by RT-PCR. Then RFP-sh-Hic-5 was transfected into osteosarcoma cell lines. The effect of Hic-5 on cell viability, proliferation and apoptosis were assessed by MTT, EdU kit and Flow cytometry. The exosomes were...

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Détails bibliographiques
Publié dans:Aging (Albany NY)
Auteurs principaux: Sha, Liansheng, Ma, Deying, Chen, Cuili
Format: Artigo
Langue:Inglês
Publié: Impact Journals 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762460/
https://ncbi.nlm.nih.gov/pubmed/33310972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103546
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