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Application of Heparin Affinity Chromatography to Produce a Differential Vaccine without Eliciting Antibodies against the Nonstructural Proteins of the Serotype O Foot-and-Mouth Disease Viruses

Although polyethylene glycol (PEG) application is the most widely used method in removing nonstructural proteins (NSPs) for foot-and-mouth disease (FMD) vaccine production, some NSPs remaining in the antigen could elicit antibodies against these proteins after repeated vaccinations in livestock. The...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Park, Sun Young, Lee, Jung-Min, Kim, Ah-Young, Park, Sang Hyun, Kim, Jae-Seok, Kim, Hyejin, Park, Jung-Won, Park, Jong-Hyeon, Ko, Young-Joon, Park, Choi-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762290/
https://ncbi.nlm.nih.gov/pubmed/33297420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121405
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