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Anti-HER2/neu Antibody Reduces Chemotherapy-Induced Ovarian Toxicity—From Bench to Bedside

Background: Trastuzumab, a humanized anti-human epidermal growth factor receptor 2 (HER2/neu) antibody, is considered a standard treatment in addition to chemotherapy in the adjuvant setting for HER2/neu-positive breast cancer, yet its impact on fertility and ovarian reserve remains obscure. We aime...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Levi, Mattan, Goshen-Lago, Tal, Yerushalmi, Rinat, Granot, Tal, Stemmer, Salomon M., Shalgi, Ruth, Ben-Aharon, Irit
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762209/
https://ncbi.nlm.nih.gov/pubmed/33297351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8120577
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