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Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

SIMPLE SUMMARY: Thrombocytosis correlates with poor prognosis for treatment of malignant melanoma. Detailed information on how platelets modify the anti-tumoral immune response is still elusive. Analyzing the immunomodulatory capacities of platelets on huCD4(+) T cells in vitro, we were able to show...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Zimmer, Niklas, Krebs, Franziska K., Zimmer, Sophia, Mitzel-Rink, Heidrun, Kumm, Elena J., Jurk, Kerstin, Grabbe, Stephan, Loquai, Carmen, Tuettenberg, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762193/
https://ncbi.nlm.nih.gov/pubmed/33291452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123653
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