IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro

The ongoing pandemic spread of the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) demands skillful strategies for novel drug development, drug repurposing and cotreatments, in particular focusing on existing candidates of host-directed antivirals (HDAs). The developmental drug IMU...

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Publicado no:Viruses
Main Authors: Hahn, Friedrich, Wangen, Christina, Häge, Sigrun, Peter, Antonia Sophia, Dobler, Gerhard, Hurst, Brett, Julander, Justin, Fuchs, Jonas, Ruzsics, Zsolt, Überla, Klaus, Jäck, Hans-Martin, Ptak, Roger, Muehler, Andreas, Gröppel, Manfred, Vitt, Daniel, Peelen, Evelyn, Kohlhof, Hella, Marschall, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762174/
https://ncbi.nlm.nih.gov/pubmed/33291455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121394
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