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Tolerant/Persister Cancer Cells and the Path to Resistance to Targeted Therapy

The capacity of cancer to adapt to treatment and evolve is a major limitation for targeted therapies. While the role of new acquired mutations is well-established, recent findings indicate that resistance can also arise from subpopulations of tolerant/persister cells that survive in the presence of...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Swayden, Mirna, Chhouri, Houssein, Anouar, Youssef, Grumolato, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761971/
https://ncbi.nlm.nih.gov/pubmed/33291749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122601
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