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Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC, also known as pancreatic cancer) is one of the deadliest tumor types, characterized by poor prognosis, profound chemoresistance and overall low survival. Gemcitabine remains the standard of care for all stages of PDAC, however, with poor clinic...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Amrutkar, Manoj, Vethe, Nils Tore, Verbeke, Caroline S., Aasrum, Monica, Finstadsveen, Anette Vefferstad, Sántha, Petra, Gladhaug, Ivar P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761836/
https://ncbi.nlm.nih.gov/pubmed/33287390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123628
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