Effect of Expression of Human Glucosylceramidase 2 Isoforms on Lipid Profiles in COS-7 Cells

Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of alternative splicing. To understand which GBA2 isofo...

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Bibliographic Details
Published in:Metabolites
Main Authors: Jatooratthawichot, Peeranat, Talabnin, Chutima, Ngiwsara, Lukana, Rustam, Yepy Hardi, Svasti, Jisnuson, Reid, Gavin E., Ketudat Cairns, James R.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761373/
https://ncbi.nlm.nih.gov/pubmed/33261081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10120488
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