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Targeted Protein Degradation Tools: Overview and Future Perspectives

SIMPLE SUMMARY: Gene inactivation is a powerful strategy to study the function of specific proteins in the context of cellular physiology that can be applied for only non-essential genes since their DNA sequence is destroyed. On the other hand, perturbing the amount of the transcript can lead to inc...

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Publicat a:Biology (Basel)
Autors principals: Prozzillo, Yuri, Fattorini, Gaia, Santopietro, Maria Virginia, Suglia, Luigi, Ruggiero, Alessandra, Ferreri, Diego, Messina, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761331/
https://ncbi.nlm.nih.gov/pubmed/33256092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology9120421
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