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The DDX23 Negatively Regulates Translation and Replication of Foot-and-Mouth Disease Virus and Is Degraded by 3C Proteinase

DEAD-box helicase 23 (DDX23) is a host nuclear helicase, which is a part of the spliceosomal complex and involved in pre-mRNA splicing. To investigate whether DDX23, an internal ribosomal entry sites transacting factor (ITAF) affects foot-and-mouth disease virus (FMDV) replication and translation th...

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Библиографические подробности
Опубликовано в: :Viruses
Главные авторы: Abdullah, Sahibzada Waheed, Han, Shichong, Wu, Jin’en, Zhang, Yun, Bai, Manyuan, Jin, Ye, Zhi, Xiaoying, Guan, Junyong, Sun, Shiqi, Guo, Huichen
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760909/
https://ncbi.nlm.nih.gov/pubmed/33255534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121348
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