STAT3 and STAT5B Mutations in T/NK-Cell Chronic Lymphoproliferative Disorders of Large Granular Lymphocytes (LGL): Association with Disease Features

SIMPLE SUMMARY: STAT3 and STAT5B mutations have been identified in a subset of T and NK large granular lymphocytic leukemia (T/NK-LGLL). The aim of our study was to evaluate the frequency and type of these mutations in all different subtypes of T/NK-LGL expansions (n = 100 patients), as well as to a...

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Publicado no:Cancers (Basel)
Main Authors: Muñoz-García, Noemí, Jara-Acevedo, María, Caldas, Carolina, Bárcena, Paloma, López, Antonio, Puig, Noemí, Alcoceba, Miguel, Fernández, Paula, Villamor, Neus, Flores-Montero, Juan A., Gómez, Karoll, Lemes, María Angelina, Hernández, Jose Carlos, Álvarez-Twose, Iván, Guerra, Jose Luis, González, Marcos, Orfao, Alberto, Almeida, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760806/
https://ncbi.nlm.nih.gov/pubmed/33255665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123508
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