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Deep Learning for Prediction and Optimization of Fast-Flow Peptide Synthesis

[Image: see text] The chemical synthesis of polypeptides involves stepwise formation of amide bonds on an immobilized solid support. The high yields required for efficient incorporation of each individual amino acid in the growing chain are often impacted by sequence-dependent events such as aggrega...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Mohapatra, Somesh, Hartrampf, Nina, Poskus, Mackenzie, Loas, Andrei, Gómez-Bombarelli, Rafael, Pentelute, Bradley L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760468/
https://ncbi.nlm.nih.gov/pubmed/33376788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c00979
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