Amyloid β-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer’s Disease-Related Models

Recent findings have shown that the connectivity and crosstalk between mitochondria and the endoplasmic reticulum (ER) at mitochondria–ER contact sites (MERCS) are altered in Alzheimer’s disease (AD) and in AD-related models. MERCS have been related to the initial steps of autophagosome formation as...

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Veröffentlicht in:Cells
Hauptverfasser: Leal, Nuno Santos, Dentoni, Giacomo, Schreiner, Bernadette, Naia, Luana, Piras, Antonio, Graff, Caroline, Cattaneo, Antonio, Meli, Giovanni, Hamasaki, Maho, Nilsson, Per, Ankarcrona, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760163/
https://ncbi.nlm.nih.gov/pubmed/33260715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122552
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