Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development

SIMPLE SUMMARY: Neuropilin-1 is a co-receptor for semaphorins and vascular endothelial growth factor family members. Neuropilin-1 can be expressed on tumor cells, tumor-infiltrating myeloid and lymphoid cells and has been linked to a tumor-promoting environment. We investigated nanobodies (Nbs) targ...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: De Vlaeminck, Yannick, Bonelli, Stefano, Awad, Robin Maximilian, Dewilde, Maarten, Rizzolio, Sabrina, Lecocq, Quentin, Bolli, Evangelia, Santos, Ana Rita, Laoui, Damya, Schoonooghe, Steve, Tamagnone, Luca, Goyvaerts, Cleo, Mazzone, Massimiliano, Breckpot, Karine, Van Ginderachter, Jo A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760077/
https://ncbi.nlm.nih.gov/pubmed/33266104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123582
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