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POCU1b, the n-Butanol Soluble Fraction of Polygoni Cuspidati Rhizoma et Radix, Attenuates Obesity, Non-Alcoholic Fatty Liver, and Insulin Resistance via Inhibitions of Pancreatic Lipase, cAMP-Dependent PDE Activity, AMPK Activation, and SOCS-3 Suppression

This study investigated the effects of the n-BuOH soluble fraction of Polygoni Cuspidati 80% ethanol extract (POCU1b) on high-fat diet (HFD)-induced obesity, non-alcoholic fatty liver (NAFL), and insulin resistance (IR) to find a safe and more effective agent. HPLC profiling of POCU1b identified sev...

詳細記述

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書誌詳細
出版年:Nutrients
主要な著者: Kim, Junghyun, Kim, Chan-Sik, Jo, Kyuhyung, Lee, Ik Soo, Kim, Joo-Hwan, Kim, Jin Sook
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759958/
https://ncbi.nlm.nih.gov/pubmed/33255404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12123612
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