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Characterization of In Vitro 3D Cell Model Developed from Human Hepatocellular Carcinoma (HepG2) Cell Line

In genetic toxicology, there is a trend against the increased use of in vivo models as highlighted by the 3R strategy, thus encouraging the development and implementation of alternative models. Two-dimensional (2D) hepatic cell models, which are generally used for studying the adverse effects of che...

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Publicado en:Cells
Autores principales: Štampar, Martina, Breznik, Barbara, Filipič, Metka, Žegura, Bojana
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759933/
https://ncbi.nlm.nih.gov/pubmed/33260628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122557
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