CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With Streptococcus pneumoniae Meningitis

BACKGROUND: Mortality from bacterial meningitis, predominately caused by Streptococcus pneumoniae, exceeds 50% in sub-Saharan African countries with high HIV prevalence. Underlying causes of high mortality are poorly understood. We examined the host and pathogen proteome in the CSF of adults with pr...

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Pubblicato in:Front Cell Infect Microbiol
Autori principali: Wall, Emma C., Brownridge, Philip, Laing, Gavin, Terra, Vanessa S., Mlozowa, Veronica, Denis, Brigitte, Nyirenda, Mulinda, Allain, Theresa, Ramos-Sevillano, Elisa, Carrol, Enitan, Collins, Andrea, Gordon, Stephen B., Lalloo, David G., Wren, Brendan, Beynon, Robert, Heyderman, Robert S., Brown, Jeremy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cellular and Infection Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759504/
https://ncbi.nlm.nih.gov/pubmed/33363056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.603623
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