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An Essential Requirement for Fgf10 in Pinna Extension Sheds Light on Auricle Defects in LADD Syndrome

The pinna (or auricle) is part of the external ear, acting to capture and funnel sound toward the middle ear. The pinna is defective in a number of craniofacial syndromes, including Lacrimo-auriculo-dento-digital (LADD) syndrome, which is caused by mutations in FGF10 or its receptor FGFR2b. Here we...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Zhang, Yang, Fons, Juan M., Hajihosseini, Mohammad K., Zhang, Tianyu, Tucker, Abigail S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758485/
https://ncbi.nlm.nih.gov/pubmed/33363172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.609643
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