Interplay of cholesterol, membrane bilayers and the AT1R: A cholesterol consensus motif on AT1R is revealed

Hypertension, mediated by the Angiotensin II receptor type 1 (AT1R), is still the major cause of premature death despite the discovery of novel therapeutics, highlighting the importance of an in depth understanding of the drug-AT1R recognition mechanisms coupled with the impact of the membrane envir...

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Bibliografische gegevens
Gepubliceerd in:Comput Struct Biotechnol J
Hoofdauteurs: Kiriakidi, Sofia, Chatzigiannis, Christos, Papaemmanouil, Christina, Tzakos, Andreas G., Cournia, Zoe, Mavromoustakos, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Research Network of Computational and Structural Biotechnology 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758360/
https://ncbi.nlm.nih.gov/pubmed/33384858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.11.042
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