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On the emergence of P-Loop NTPase and Rossmann enzymes from a Beta-Alpha-Beta ancestral fragment

This article is dedicated to the memory of Michael G. Rossmann. Dating back to the last universal common ancestor, P-loop NTPases and Rossmanns comprise the most ubiquitous and diverse enzyme lineages. Despite similarities in their overall architecture and phosphate binding motif, a lack of sequence...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Longo, Liam M, Jabłońska, Jagoda, Vyas, Pratik, Kanade, Manil, Kolodny, Rachel, Ben-Tal, Nir, Tawfik, Dan S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758060/
https://ncbi.nlm.nih.gov/pubmed/33295875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64415
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