Inhibition of Cyclin-dependent Kinase (CDK) Decreased Survival of NB4 Leukemic Cells: Proposing a p53-Independent Sensitivity of Leukemic Cells to Multi-CDKs Inhibitor AT7519

An unbounded number of events exist beneath the intricacy of each particular hematologic malignancy, prompting the tumor cells into an unrestrained proliferation and invasion. Aberrant expression of cyclin-dependent kinases (CDKs) is one of these events which disrupts the regulation of cell cycle an...

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Vydáno v:Iran J Pharm Res
Hlavní autoři: Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Shanaki, Mehrnoosh, Yousefi, Amir-Mohammad, Anjam Najmedini, Ali, Bashash, Davood
Médium: Artigo
Jazyk:Inglês
Vydáno: Shaheed Beheshti University of Medical Sciences 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7758003/
https://ncbi.nlm.nih.gov/pubmed/33680018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2020.113170.14148
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