Involvement of N- and C-terminal region of recombinant cervid prion protein in its reactivity to CWD and atypical BSE prions in real-time quaking-induced conversion reaction in the presence of high concentrations of tissue homogenates

The real-time quaking-induced conversion (RT-QuIC) reaction is a sensitive and specific method for detecting prions. However, inhibitory factors present in tissue homogenates can easily interfere with this reaction. To identify the RT-QuIC condition under which low levels of chronic wasting disease...

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Bibliographic Details
Published in:Prion
Main Authors: Suzuki, Akio, Sawada, Kazuhei, Yamasaki, Takeshi, Denkers, Nathaniel D, Mathiason, Candace K, Hoover, Edward A, Horiuchi, Motohiro
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757825/
https://ncbi.nlm.nih.gov/pubmed/33345717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2020.1858694
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