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Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice
The advent of tools enabling the direct manipulation of microglia has furthered our understanding of their role in health and disease. Here, we present a detailed protocol allowing for microglia turnover in adult CX(3)CR(1)(creERT2) × iDTR or CX(3)CR(1)(creERT2) × iDTR × tdTomato(flox) mice, either...
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| Publicado no: | STAR Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7757678/ https://ncbi.nlm.nih.gov/pubmed/33377105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100211 |
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