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New Insights into the Phage Genetic Switch: Effects of Bacteriophage Lambda Operator Mutations on DNA Looping and Regulation of P(R), P(L), and P(RM)

One of the best understood systems in genetic regulatory biology is the so-called “genetic switch” that determines the choice the phage-encoded CI repressor binds cooperatively to tripartite operators, O(L) and O(R), in a defined pattern, thus blocking the transcription at two lytic promoters, P(L)...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Lewis, Dale E.A., Gussin, Gary N., Adhya, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757127/
https://ncbi.nlm.nih.gov/pubmed/27670714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.08.027
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