Involvement of Blnk and Foxo1 in tumor suppression in BCR-ABL1-transformed pro-B cells

Oncogenic Bcr-Abl kinase mimics pre-B cell receptor (pre-BCR) survival signals in BCR-ABL1-positive B-cell acute lymphoblastic leukemia (BCR-ABL1(+) B-ALL), driving B-cell progenitor malignant transformation; thus, defining a particularly unfavorable prognosis for patients. During B-cell development...

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Publicado en:Oncol Rep
Autores principales: Zhang, Ping, Wang, Yang, Qin, Mengting, Li, Dandan, Odhiambo, Woodvine Otieno, Yuan, Meng, Lv, Zhuangwei, Liu, Chengcheng, Ma, Yunfeng, Dong, Yanying, Ji, Yanhong
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2021
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757083/
https://ncbi.nlm.nih.gov/pubmed/33416167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7888
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