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Asymmetric Biocatalytic Synthesis of 1‐Aryltetrahydro‐β‐carbolines Enabled by “Substrate Walking”

Stereoselective catalysts for the Pictet–Spengler reaction of tryptamines and aldehydes may allow a simple and fast approach to chiral 1‐substituted tetrahydro‐β‐carbolines. Although biocatalysts have previously been employed for the Pictet–Spengler reaction, not a single one accepts benzaldehyde an...

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Xehetasun bibliografikoak
Argitaratua izan da:Chemistry
Egile Nagusiak: Eger, Elisabeth, Schrittwieser, Joerg H., Wetzl, Dennis, Iding, Hans, Kuhn, Bernd, Kroutil, Wolfgang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756766/
https://ncbi.nlm.nih.gov/pubmed/33017078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004449
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