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Upregulated LRRC55 promotes BK channel activation and aggravates cell injury in podocytes
Podocyte injury is a common hallmark in various glomerular diseases. The level of LRRC55 was increased in podocytes of patients with focal segmental glomerulosclerosis (FSGS), diabetic nephropathy (DN), and membranous nephropathy (MN). Upregulated LRRC55 and increased intracellular Ca(2+) led to BK...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7756252/ https://ncbi.nlm.nih.gov/pubmed/33346797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192373 |
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