IL-33 triggers early eosinophil-dependent events leading to metaplasia in a chronic model of gastritis-prone mice

BACKGROUND & AIMS. IL-33/IL-1F11 is an important mediator for the development of Th2-driven inflammatory disorders and has also been implicated in the pathogenesis of GI-related cancers, including gastric carcinoma. We therefore sought to mechanistically determine IL-33’s potential role as a cri...

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Publicado no:Gastroenterology
Main Authors: De Salvo, Carlo, Pastorelli, Luca, Petersen, Christine P., Buttò, Ludovica F., Buela, Kristine-Ann, Omenetti, Sara, Locovei, Silviu A., Ray, Shuvra, Friedman, Hannah R., Duijser, Jacob, Xin, Wei, Osme, Abdullah, Cominelli, Fabio, Mahabeleshwar, Ganapati H., Mills, Jason C., Goldenring, James R., Pizarro, Theresa T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755675/
https://ncbi.nlm.nih.gov/pubmed/33010253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.09.040
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