PD-L1 Is a Tumor Suppressor in Aggressive Endometrial Cancer Cells and Its Expression Is Regulated by miR-216a and lncRNA MEG3

BACKGROUND: Poorly differentiated endometrioid adenocarcinoma and serous adenocarcinoma represent an aggressive subtype of endometrial cancer (EC). Programmed death-ligand-1 (PD-L1) was known to exhibit a tumor cell-intrinsic function in mediating immune-independent tumor progression. However, the f...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Xu, Daozhi, Dong, Peixin, Xiong, Ying, Chen, Rui, Konno, Yosuke, Ihira, Kei, Yue, Junming, Watari, Hidemichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755603/
https://ncbi.nlm.nih.gov/pubmed/33363153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.598205
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