Lanean...
What one lipid giveth, another taketh away
Acid sphingomyelinase deficiency, which prevents degradation of sphingomyelin (SM), causes lysosomal SM overload both in mice and in patients with Niemann–Pick disease A or B. Altered cellular SM homeostasis disrupts the development and function of natural killer T cells by obstructing the presentat...
Gorde:
| Argitaratua izan da: | Nat Immunol |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7755123/ https://ncbi.nlm.nih.gov/pubmed/31636467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0525-8 |
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