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Dantrolene : From Malignant Hyperthermia to Alzheimer’s Disease
BACKGROUND & OBJECTIVE: Dantrolene, a ryanodine receptor antagonist, is primarily known as the only clinically acceptable and effective treatment for malignant hyperthermia (MH). Inhibition of ryanodine receptor (RyR) by dantrolene decreases the abnormal calcium release from the sarcoplasmic ret...
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| Publicado en: | CNS Neurol Disord Drug Targets |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7754833/ https://ncbi.nlm.nih.gov/pubmed/29921212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1871527317666180619162649 |
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