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Understanding adverse events of immunotherapy: A mechanistic perspective

The treatment of many cancers has been revolutionized by immune checkpoint blockade (ICB) as a standard-of-care therapeutic. Despite many successes, a large proportion of patients treated with ICB agents experience immune-related adverse events (irAEs) in the form of clinical autoimmunity, ranging f...

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Pubblicato in:J Exp Med
Autori principali: Burke, Kelly P., Grebinoski, Stephanie, Sharpe, Arlene H., Vignali, Dario A.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754677/
https://ncbi.nlm.nih.gov/pubmed/33601411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192179
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