IL‐1β/IL‐1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha‐Synuclein pathology in the olfactory bulb, substantia nigra and striatum

Olfactory dysfunction is one of the early symptoms seen in Parkinson’s disease (PD). However, the mechanisms underlying olfactory pathology that impacts PD disease progression and post‐mortem appearance of alpha‐Synuclein (α‐Syn) inclusions in and beyond olfactory bulb in PD remain unclear. It has b...

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Bibliographic Details
Published in:Brain Pathol
Main Authors: Niu, Haichen, Wang, Qian, Zhao, Weiguang, Liu, Jianxin, Wang, Deguang, Muhammad, Bilal, Liu, Xiaoyu, Quan, Ning, Zhang, Haoyu, Zhang, Fang, Wang, Yong, Li, Haiying, Yang, Rongli
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754320/
https://ncbi.nlm.nih.gov/pubmed/32678959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12886
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