IL‐1β/IL‐1R1 signaling induced by intranasal lipopolysaccharide infusion regulates alpha‐Synuclein pathology in the olfactory bulb, substantia nigra and striatum

Olfactory dysfunction is one of the early symptoms seen in Parkinson’s disease (PD). However, the mechanisms underlying olfactory pathology that impacts PD disease progression and post‐mortem appearance of alpha‐Synuclein (α‐Syn) inclusions in and beyond olfactory bulb in PD remain unclear. It has b...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Niu, Haichen, Wang, Qian, Zhao, Weiguang, Liu, Jianxin, Wang, Deguang, Muhammad, Bilal, Liu, Xiaoyu, Quan, Ning, Zhang, Haoyu, Zhang, Fang, Wang, Yong, Li, Haiying, Yang, Rongli
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754320/
https://ncbi.nlm.nih.gov/pubmed/32678959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12886
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