Ginsenoside Compound K Regulates HIF-1α-Mediated Glycolysis Through Bclaf1 to Inhibit the Proliferation of Human Liver Cancer Cells

This study aimed to demonstrate that ginsenoside compound K (20 (S)-ginsenoside CK; CK) downregulates Bcl-2-associated transcription factor 1 (Bclaf1), which inhibits the hypoxia-inducible factor-1α (HIF-1α)-mediated glycolysis pathway to inhibit the proliferation of liver cancer cells. Treatment of...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhang, Silin, Zhang, Meilan, Chen, Jiaxin, Zhao, Jiaqi, Su, Jielin, Zhang, Xuewu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753211/
https://ncbi.nlm.nih.gov/pubmed/33363466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.583334
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