Polysaccharide of Atractylodes macrocephala Koidz (PAMK) Alleviates Cyclophosphamide-induced Immunosuppression in Mice by Upregulating CD28/IP3R/PLCγ-1/AP-1/NFAT Signal Pathway

The polysaccharide of Atractylodes macrocephala Koidz (PAMK) is recognized as an immune enhancer, with anti-cancer, anti-tumour, lymphocyte-activating and lymphocytes proliferation-inducing effects. For investigating the mechanism that PAMK alleviates the decline in T cell activation induced by CTX,...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Xiang, Xuelian, Cao, Nan, Chen, Feiyue, Qian, Long, Wang, Yifei, Huang, Yunmao, Tian, Yunbo, Xu, Danning, Li, Wanyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753208/
https://ncbi.nlm.nih.gov/pubmed/33363462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.529657
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