Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels

BACKGROUND: Dolutegravir (DTG) is a preferred regimen for all people with HIV including pregnant women, but its effects on the fetus are not fully understood. Periconceptional exposure to DTG has been associated with increased rates of neural tube defects (NTDs), although it is unknown whether this...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: Mohan, Haneesha, Lenis, Monica Guzman, Laurette, Evelyn Y., Tejada, Oscar, Sanghvi, Tanvi, Leung, Kit-Yi, Cahill, Lindsay S., Sled, John G., Delgado-Olguín, Paul, Greene, Nicholas D.E., Copp, Andrew J., Serghides, Lena
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753150/
https://ncbi.nlm.nih.gov/pubmed/33341441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103167
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky