Atractylenolide-I Suppresses Tumorigenesis of Breast Cancer by Inhibiting Toll-Like Receptor 4-Mediated Nuclear Factor-κB Signaling Pathway

Background: Toll-like receptor 4 (TLR4) is an essential sensor related to tumorigenesis, and overexpression of TLR4 in human tumors often correlates with poor prognosis. Atractylenolide‐I (AT-I), a novel TLR4-antagonizing agent, is a major bioactive component from Rhizoma Atractylodes Macrocephalae....

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Long, Fangyi, Lin, Hong, Zhang, Xiqian, Zhang, Jianhui, Xiao, Hongtao, Wang, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753112/
https://ncbi.nlm.nih.gov/pubmed/33363472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.598939
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