Biosynthesis of Random-Homo Block Copolymer Poly[Glycolate-ran-3-Hydroxybutyrate (3HB)]-b-Poly(3HB) Using Sequence-Regulating Chimeric Polyhydroxyalkanoate Synthase in Escherichia coli

Glycolate (GL)-containing polyhydroxyalkanoate (PHA) was synthesized in Escherichia coli expressing the engineered chimeric PHA synthase PhaC(AR) and coenzyme A transferase. The cells produced poly[GL-co-3-hydroxybutyrate (3HB)] with the supplementation of GL and 3HB, thus demonstrating that PhaC(AR...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Arai, Shuzo, Sakakibara, Sayaka, Mareschal, Robin, Ooi, Toshihiko, Zinn, Manfred, Matsumoto, Ken’ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752996/
https://ncbi.nlm.nih.gov/pubmed/33364233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.612991
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