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Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group by Nanopore Sequencing

Chemically induced DNA adducts can lead to mutations and cancer. Unfortunately, because common analytical methods (e.g., liquid chromatography-mass spectrometry) require adducts to be digested or liberated from DNA before quantification, information about their positions within the DNA sequence is l...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Nookaew, Intawat, Jenjaroenpun, Piroon, Du, Hua, Wang, Pengcheng, Wu, Jun, Wongsurawat, Thidathip, Moon, Sun Hee, Huang, En, Wang, Yinsheng, Boysen, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752846/
https://ncbi.nlm.nih.gov/pubmed/32799528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.0c00202
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