E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice

Nicotine exposure increases the release of glutamate in part through stimulatory effects on pre-synaptic nicotinic acetylcholine receptors (nAChRs). To assess the impact of chronic electronic (e)-cigarette use on these drug dependence pathways, we exposed C57BL/6 mice to three types of inhalant expo...

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Pubblicato in:Chem Biol Interact
Autori principali: Alasmari, Fawaz, Alexander, Laura Crotty E., Hammad, Alaa M., Horton, Austin, Alhaddad, Hasan, Schiefer, Isaac T., Shin, John, Moshensky, Alexander, Sari, Youssef
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752837/
https://ncbi.nlm.nih.gov/pubmed/33242460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2020.109308
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