Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity

OBJECTIVES: Altered enteroendocrine cell (EEC) function in obesity and type 2 diabetes is not fully understood. Understanding the transcriptional program that controls EEC differentiation is important because some EEC types harbor significant therapeutic potential for type 2 diabetes. METHODS: EEC i...

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Publicado en:Int J Obes (Lond)
Main Authors: Osinski, Céline, Le Gléau, Léa, Poitou, Christine, de Toro-Martin, Juan, Genser, Laurent, Fradet, Magali, Soula, Hédi Antoine, Leturque, Armelle, Blugeon, Corinne, Jourdren, Laurent, Hubert, Edwige Ludiwyne, Clément, Karine, Serradas, Patricia, Ribeiro, Agnès
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752761/
https://ncbi.nlm.nih.gov/pubmed/33037328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-020-00694-1
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