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Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations

OBJECTIVES: To determine the prevalence of Melanocortin-4 Receptor (MC4R) mutations in a cohort of children and adolescents with overweight or obesity and to determine whether treatment responses differed between carriers and noncarriers. METHODS: Using target region capture sequencing, an MC4R muta...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Trier, Cæcilie, Hollensted, Mette, Schnurr, Theresia M., Lund, Morten Asp Vonsild, Nielsen, Tenna Ruest Haarmark, Rui, Gao, Andersson, Ehm Astrid, Svendstrup, Mathilde, Bille, Dorthe Sadowa, Gjesing, Anette P., Fonvig, Cilius Esmann, Frithioff-Bøjsøe, Christine, Balslev-Harder, Marie, Quan, Shi, Gamborg, Michael, Pedersen, Oluf, Ängquist, Lars, Holm, Jens-Christian, Hansen, Torben
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752754/
https://ncbi.nlm.nih.gov/pubmed/32921795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-020-00673-6
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