Weight loss normalizes enhanced expression of the oncogene survivin in visceral adipose tissue and blood leukocytes from individuals with obesity

BACKGROUND/OBJECTIVES: Survivin is an oncogene associated with a decrease in apoptosis, an increase in tumor growth, and poor clinical outcome of diverse malignancies. A correlation between obesity, cancer, and survivin is reported in the literature. To date, the impact of weight loss on change in s...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Izquierdo, Andrea G., Carreira, Marcos C., Rodriguez-Carnero, Gemma, Fernandez-Quintela, Alfredo, Sueiro, Aurelio M., Martinez-Olmos, Miguel A., Guzman, German, De Luis, Daniel, Pinhel, Marcela A. S., Nicoletti, Carolina F., Nonino, Carla B., Ortega, Francisco J., Portillo, Maria P., Fernandez-Real, Jose M., Casanueva, Felipe F., Crujeiras, Ana B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752753/
https://ncbi.nlm.nih.gov/pubmed/32546857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-020-0630-7
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