High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring: the GUSTO cohort

BACKGROUND/OBJECTIVES: Maternal glycaemia promotes fetal adiposity. Inositol, an insulin sensitizer, has been trialled for gestational diabetes prevention. The placenta has been implicated in how maternal hyperglycaemia generates fetal pathophysiology, but no studies have examined whether placental...

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Publicat a:Int J Obes (Lond)
Autors principals: Chu, Anne H. Y., Tint, Mya T., Chang, Hsin F., Wong, Gerard, Yuan, Wen Lun, Tull, Dedreia, Nijagal, Brunda, Narayana, Vinod K., Meikle, Peter J., Chang, Kenneth T. E., Lewis, Rohan M., Chi, Claudia, Yap, Fabian K. P., Tan, Kok Hian, Shek, Lynette P., Chong, Yap-Seng, Gluckman, Peter D., Lee, Yung Seng, Fortier, Marielle V., Godfrey, Keith M., Eriksson, Johan G., Karnani, Neerja, Chan, Shiao-Yng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752752/
https://ncbi.nlm.nih.gov/pubmed/32433604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-020-0596-5
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